✦ LIBER ✦

Synthesis and Biological Evaluation of 2,4-Diamino-6-(arylaminomethyl)pyrido[2,3- d ]pyrimidines as Inhibitors of Pneumocystis c arinii and Toxoplasma g ondii Dihydrofolate Reductase and as Antiopportunistic Infection and Antitumor Agents 1

✍ Scribed by Gangjee, Aleem; Adair, Ona O.; Queener, Sherry F.

Book ID: 127290935
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 120 KB
Volume: 46
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm030312n

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pneumocystis c arinii and Toxoplasma g o

Pneumocystis c arinii and Toxoplasma g ondii Dihydrofolate Reductase Inhibitors and Antitumor Agents: Synthesis and Biological Activities of 2,4-Diamino-5-methyl-6-[(monosubstituted anilino)methyl]- pyrido[2,3- d ]pyrimidines 1

✍ Gangjee, Aleem; Adair, Ona; Queener, Sherry F. 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 128 KB

Synthesis of 2,4-Diamino-6-[2‘- O -(ω-ca

Synthesis of 2,4-Diamino-6-[2‘- O -(ω-carboxyalkyl)oxydibenz[ b , f ]azepin-5-yl]methylpteridines as Potent and Selective Inhibitors of Pneumocystis c arinii, Toxoplasma g ondii , and Mycobacterium a vium Dihydrofolate Reductase

✍ Rosowsky, Andre; Fu, Hongning; Chan, David C. M.; Queener, Sherry F. 📂 Article 📅 2004 🏛 American Chemical Society 🌐 English ⚖ 286 KB

Design, synthesis and biological evaluat

Design, synthesis and biological evaluation of 2,4-diamino-6-methyl-5-substitutedpyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors

✍ Aleem Gangjee; Hiteshkumar D. Jain; Sherry F. Queener 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 75 KB

Nine novel nonclassical 2,4-diamino-6-methyl-5-thioarylsubstituted-7H-pyrrolo [2,3-d]pyrimidines 2-10 were synthesized as potential inhibitors of dihydrofolate reductase and as antitumor agents. The analogues contain various electron donating and electron withdrawing substituents on the phenylsulfan

6-Substituted 2,4-Diaminopyrido[3,2- d ]

6-Substituted 2,4-Diaminopyrido[3,2- d ]pyrimidine Analogues of Piritrexim as Inhibitors of Dihydrofolate Reductase from Rat Liver, Pneumocystis carinii , and Toxoplasma gondii and as Antitumor Agents 1

✍ Gangjee, Aleem; Zhu, Yuanming; Queener, Sherry F. 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 173 KB

Design, Synthesis and Biological Evaluat

Design, Synthesis and Biological Evaluation of 2,4-Diamino-6-methyl-5-substituted-pyrrolo[2,3-d]pyrimidines as Dihydrofolate Reductase Inhibitors.

✍ Aleem Gangjee; Hiteshkumar D. Jain; Sherry F. Queener 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

Selective Pneumocystis carinii Dihydrofo

Selective Pneumocystis carinii Dihydrofolate Reductase Inhibitors: Design, Synthesis, and Biological Evaluation of New 2,4-Diamino-5-substituted-furo[2,3- d ]pyrimidines 1

✍ Gangjee, Aleem; Guo, Xin; Queener, Sherry F.; Cody, Vivian; Galitsky, Nikolai; L 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 152 KB