๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Selective Pneumocystis carinii Dihydrofolate Reductase Inhibitors: Design, Synthesis, and Biological Evaluation of New 2,4-Diamino-5-substituted-furo[2,3- d ]pyrimidines 1

โœ Scribed by Gangjee, Aleem; Guo, Xin; Queener, Sherry F.; Cody, Vivian; Galitsky, Nikolai; Luft, Joe R.; Pangborn, Walter


Book ID
126035581
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
152 KB
Volume
41
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Design, synthesis and biological evaluat
โœ Aleem Gangjee; Hiteshkumar D. Jain; Sherry F. Queener ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 75 KB

Nine novel nonclassical 2,4-diamino-6-methyl-5-thioarylsubstituted-7H-pyrrolo [2,3-d]pyrimidines 2-10 were synthesized as potential inhibitors of dihydrofolate reductase and as antitumor agents. The analogues contain various electron donating and electron withdrawing substituents on the phenylsulfan