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Synthesis and biological evaluation of 14,15-dehydro-LTA4 analog

✍ Scribed by Mylène Garcia; Thierry Durand; Jean Claude Rossi; Simona Zarini; Manlio Bolla; Giancarlo Folco; Pat Wheelan; Angelo Sala

Book ID
104364741
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
184 KB
Volume
7
Category
Article
ISSN
0960-894X

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✦ Synopsis

New stable leukotriene A4 analog with acetylenic function in positions 14,15 has been synthesized. Conversion of this analog to the corresponding LTC4 derivative and the structural and biological characterization are presented.

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