The synthesis and biological evaluation of 4-(4-(alkyl- and phenylaminocarbonyl)benzoyl)benzoic acids (4a-4d) as non-steroidal inhibitors of steroid 5 alpha-reductase are described. The compounds were tested in vitro for inhibitory activity toward rat and human 5 alpha-reductase isozymes 1 and 2 at
✦ LIBER ✦
Synthesis and Biochemical Evaluation of (Carbamoylalkenyl)phenyloxy Carboxylic Acid Derivatives as Non-steroidal 5α-Reductase Inhibitors
✍ Scribed by Lars Kattner; Sigrid Göhring; Rolf W. Hartmann
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 561 KB
- Volume
- 328
- Category
- Article
- ISSN
- 0365-6233
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