ChemInform Abstract: 5-Phenyl Substituted 1-Methyl-2-pyridones and 4′-Substituted Biphenyl-4-carboxylic Acids. Synthesis and Evaluation as Inhibitors of Steroid-5α-reductase Type 1 and 2.
✍ Scribed by Franck Picard; Tobias Schulz; Rolf W. Hartmann
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 39 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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The synthesis and biological evaluation of 4-(4-(alkyl- and phenylaminocarbonyl)benzoyl)benzoic acids (4a-4d) as non-steroidal inhibitors of steroid 5 alpha-reductase are described. The compounds were tested in vitro for inhibitory activity toward rat and human 5 alpha-reductase isozymes 1 and 2 at
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v