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Synthesis and antiviral evaluation of new 2,5-disubstituted 1,3,4-oxadiazole derivatives and their acyclic nucleoside analogues

✍ Scribed by Wael A. El-Sayed; Farag A. El-Essawy; Omar M. Ali; Barsis S. Nasr; Mohamed M. Abdalla; Adel A.-H. Abdel-Rahman


Publisher
Springer Vienna
Year
2010
Tongue
English
Weight
270 KB
Volume
141
Category
Article
ISSN
0026-9247

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✍ Wael A. El-Sayed; Omar M. Ali; Hend A. Hendy; Adel A.-H. Abdel-Rahman πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 354 KB πŸ‘ 1 views

## Abstract A series of new 2,5‐disubstituted‐1,3,4‐oxadiazole and 1,2,4‐triazole derivatives were synthesized by heterocyclization of acid hydrazide **1** and thiosemicarbazide derivative **2**. Furthermore, the acyclic __C__‐nucleoside analogs were prepared by cyclization of their corresponding s