𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Modelisation, synthesis and antiviral evaluation of new 2,3-disubstituted thiazolidinone nucleoside analogues

✍ Scribed by J.C. Graciet; V. Niddam; M. Gamberoni; C. Trabaud; J. Dessolin; M. Medou; N. Mourier; F. Zoulim; C. Borel; O. Hantz; M. Camplo; J.C. Chermann; J.L. Kraus


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
254 KB
Volume
6
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Synthesis and antiviral evaluation of Ξ±-
✍ Kohei Yamada; Hiroyuki Hayakawa; Shinji Sakata; Noriyuki Ashida; Yuichi Yoshimur πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 427 KB

We have identified a selective S(N)2' reaction triggered by iodide ion that leads to the ring-opening of 2,2'-anhydro-Ξ±-nucleosides. By applying the method, we have synthesized Ξ±-D-2',3'-didehydro-2',3'-dideoxy-3'-C-hydroxymethyl nucleosides, designed as potential antiviral agents.