Synthesis and antiviral activity of new unsaturated pyrimidine acyclonucleosides
β Scribed by A. A. Ozerov; M. S. Novikov; A. K. Brel'; O. T. Andreeva; G. V. Vladykov; E. I. Boreko; L. V. Korobchenko; S. G. Vervetchenko
- Book ID
- 111988954
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 452 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0091-150X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract A number of __N__βsubstituted pyrimidine glycosides were synthesized by coupling reaction of the pyrimidine base with acetobromosugars followed by deprotection. The synthesized compounds were tested for their antiviral activity against Hepatitis B Virus (HBV). Plaque reduction infectivi
Synthesis and Antiviral Activity of Novel Aza-acyclonucleosides. -Using Mitsunobu coupling conditions the novel title compounds (VII) and (IX) are prepared.Surprisingly, they are avoid of any antiviral activity.