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Synthesis and antiviral activity of N9-[β-D-arabinofuranosyl]guanine

✍ Scribed by V. A. Timoshchuk; L. N. Kulinkovich; G. V. Vladyko; E. I. Boreko


Book ID
112418546
Publisher
Springer
Year
1985
Tongue
English
Weight
242 KB
Volume
19
Category
Article
ISSN
0091-150X

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Synthesis of 9-(fl-D-arabinofuranosyl)guanine (ara-G) from 1-(fl-o-arabinofuranosyl)cytosine (ara-C) and guanine, guanosine or 2'-deoxyguanosine (dG) by glutaraldehyde-treated Escherichia coli BM-11 cells is described. It is shown that the concentration of phosphate ions, molar ratio of substrates a