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Synthesis and antiviral activity of N- and O-acyl derivatives of threo-DL-phenylserine

✍ Scribed by Yu. Straukas; N. Dirvyanskite; V. E. Yavorovskaya; A. N. Evstropov; V. N. Kiseleva

Book ID
112417169
Publisher
Springer
Year
1993
Tongue
English
Weight
266 KB
Volume
27
Category
Article
ISSN
0091-150X

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✍ Juozapas Straukas; Nijole Dirvianskyte; Eugenius Butkus πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 47 KB πŸ‘ 1 views

A series of N-formyl-O-acyl-β-phenylserine derivatives 1b -7b were prepared by the interaction of N-acylβ-phenylserine ethyl esters 1a-7a with formic acid in presence of 1.5% HF. One-pot acyl group N→O migration followed N-formylation under elaborated reaction conditions. Results and Discussion