✦ LIBER ✦
One-pot Synthesis of N-Formyl-O-acyl- threo- and erythro-DL-β-phenylserine Ethyl Esters and their Antiviral Properties
✍ Scribed by Juozapas Straukas; Nijole Dirvianskyte; Eugenius Butkus
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 47 KB
- Volume
- 342
- Category
- Article
- ISSN
- 1615-4150
No coin nor oath required. For personal study only.
✦ Synopsis
A series of N-formyl-O-acyl-β-phenylserine derivatives 1b -7b were prepared by the interaction of N-acylβ-phenylserine ethyl esters 1a-7a with formic acid in presence of 1.5% HF. One-pot acyl group N→O migration followed N-formylation under elaborated reaction conditions.
Results and Discussion