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Synthesis and antiviral activity of fluorinated 3-phenyl-1,2,4-benzotriazines

✍ Scribed by S. K. Kotovskaya; G. A. Zhumabaeva; N. M. Perova; Z. M. Baskakova; V. N. Charushin; O. N. Chupakhin; E. F. Belanov; N. I. Bormotov; S. M. Balakhnin; O. A. Serova


Book ID
106491646
Publisher
Springer
Year
2007
Tongue
English
Weight
100 KB
Volume
41
Category
Article
ISSN
0091-150X

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Two-step syntheses of 3-methyl and 3-phe
✍ Mohamed Khodja; Saad Moulay; Hocine Boutoumi; Horst Wilde πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 121 KB

3-Methyl-1,2,4-benzotriazine and some of its derivatives were prepared in moderate yields (50-70%) via a reductive cyclization by a PtO 2catalyzed hydrogenation of the corresponding 2nitrophenylhydrazones of the pyruvic acid. The latter compounds were obtained in yields higher than 90% by reacting 2