Synthesis and Antimicrobiological Activity of N-Aryl-substituted 2-Methyl-3-carbethoxy-5-pyrrolinone Derivatives
✍ Scribed by Fina Lovren; Igor D. Gaon; Blanka Bobarevic
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 218 KB
- Volume
- 323
- Category
- Article
- ISSN
- 0365-6233
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✦ Synopsis
Abstract
We describe the synthesis of N‐aryl‐2‐methyl‐3‐carbethoxy‐5‐pyrrolinones benzylidene derivatives, their condensation with azomethines and substitution with aniline. The compounds have been tested for antimicrobial and fungicide activity: they have better fungicidal than bactericidal activity.
📜 SIMILAR VOLUMES
## Abstract The reaction of ethyl 4‐(benzofuran‐2‐yl)‐2,4‐dioxobutanoate **2** with two moles of hydrazine hydrate afforded 5‐(benzofuran‐2‐yl)‐1__H__‐pyrazole‐3‐carbohydrazide **4a**, while its reaction with equimolar amount of phenylhydrazine gave ester **3b** which then converted to 5‐(benzofura