✦ LIBER ✦

Synthesis and antimicrobial activity of substituted [(pyrazol-4-yl)methylene]hydrazono-2,3-dihydrothiazoles and their sugar derivatives

✍ Scribed by Adel A.-H. Abdel-Rahman; Wael A. El-Sayed; El-Sayed G. Zaki; Asem A. Mohamed; Ahmed A. Fadda

Publisher: Journal of Heterocyclic Chemistry
Year: 2011
Tongue: English
Weight: 160 KB
Volume: 49
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.668

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✦ Synopsis

Abstract

A number of new [(pyrazol‐4‐yl)methylene]hydrazono‐2,3‐dihydrothiazole derivatives, their sugar hydrazones and N‐glycosides were synthesized. Furthermore, N‐substituted oxygenated alkyl and hydroxyl derivatives and 1,3,4,‐oxadiazoline acyclic nucleoside analogs were prepared. The newly synthesized compounds were tested for their antimicrobial activities and showed moderate to high inhibition activities. J. Heterocyclic Chem., (2012).

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