Synthesis and antimicrobial activity of novel 5-amino-4-cyano-1H-pyrazole and quinazolin-4(3H)-one derivatives
✍ Scribed by Mohamed T. Abdel-Aal; Abdel-Aleem H. Abdel-Aleem; Laila I. Ibahim; Ahmed L. Zein
- Book ID
- 107642362
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 457 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0253-6269
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## Abstract magnified image A series of 1,3,4‐oxadiazolyl‐quinazolin‐4(3__H__)ones have been synthesized using known methods. All the compounds have been established on basis of elemental analysis, IR and NMR spectral data. The __in vitro__ antimicrobial screening of the synthesized compounds were
## Abstract A series of 2‐[mercapto(cyano)methylene]‐1,2,3,4‐tetrahydroquinazolin‐4‐ones and 2‐amino‐4‐methylpyrazolo[1,5‐a]quinazolin‐5(4__H__)‐one were prepared from 2‐cyanomethylquinazolin‐4(3__H__)‐ones __via__ α‐bromo derivatives 4 and amide oxime 8, respectively. The new compounds have been c