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Synthesis of 2-[mercapto(cyano)methylene]-1,2,3,4-tetrahydro-quinazolin-4-ones and 2-amino-4-methylpyrazolo-[1,5-a]quinazolin-5(4H)-one

✍ Scribed by Judit Fleischer; Kálmán Takács; István Hermecz

Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
248 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A series of 2‐[mercapto(cyano)methylene]‐1,2,3,4‐tetrahydroquinazolin‐4‐ones and 2‐amino‐4‐methylpyrazolo[1,5‐a]quinazolin‐5(4__H__)‐one were prepared from 2‐cyanomethylquinazolin‐4(3__H__)‐ones via α‐bromo derivatives 4 and amide oxime 8, respectively. The new compounds have been characterized by elemental analyses and ^1^H‐nmr, in some cases by ir and ^13^C‐nmr investigations.

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