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Synthesis and Antimicrobial Activity of Novel [(3-Aminopyrimidiniumyl)thio]methyl Cephalosporins

✍ Scribed by Kim, Yong-Zu; Lim, Jong-Chan; Yeo, Jae-Hong; Bang, Chan-Sik; Kim, Won-Sup; Kim, Sam-Sik; Woo, Yong-Min; Yang, Duck-Ho; Oh, Hunseung; Nahm, Keepyung


Book ID
111900190
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
659 KB
Volume
37
Category
Article
ISSN
0022-2623

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Synthesis and antibacterial activity of
✍ Koichi Tsuji; Koichi Yasumura; Hiroshi Ishikawa πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 171 KB

Cephalosporins with catechol-containing (pyridinium-4'-thio)methyl groups at C-3 have been synthesized and examined their antibacterial activity. They were found to have high potency against gram-negative bacteria including Pseudomonas aeruginosa. In particular, compound 9e bearing {I'-[N-(3",4"dihy