Synthesis and in vitro antimicrobial activity of 3-heteroarylsulphonylmethyl cephems: a new class of cephalosporins
β Scribed by MP Singh; R Singh; SN Maiti; P Spevak; N Ishida; A Hyodo; RG Micetich
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 807 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0223-5234
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π SIMILAR VOLUMES
A new class of methyleneamine-linked bis-heterocycles that exhibit antimicrobial activity was synthesized. Bromination of 1 followed by condensation with thiourea gave 3. The reaction of 3 with propargyl bromide in dry toluene under inert atmosphere led to the formation of 4. Its subsequent reaction
## Abstract A series of a new class of phosphorus analogue macrocycles was accomplished by condensation of Nβsubstitutedβ[bis(3,5βdimethylβ2βhydroxybenzyl)]βamines with various phosphorus dichlorides in dry toluene in the presence of triethylamine at 0β50Β°C. All the title compounds were evaluated f