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Synthesis and Antibacterial and Cytotoxic Activities of New N -3 Substituted Thiazolidine-2,4-dione Derivatives Bearing the Pyrazole Moiety

โœ Scribed by Desai, Nisheeth C.; Satodiya, Hitesh M.; Kotadiya, Ghanshyam M.; Vaghani, Hasit V.


Book ID
121727933
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
297 KB
Volume
347
Category
Article
ISSN
0365-6233

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The synthesis of a new series of 1 beta-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octane-2,4-dione moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bateria are determined and the effect of substituent on the bicyclic ring as well as st