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Synthesis and antibacterial activity of some substituted 4-quinolone-3-carboxylic acids

โœ Scribed by Markees, D. G.; Schwab, Linda S.; Vegotsky, A.


Book ID
125544503
Publisher
American Chemical Society
Year
1974
Tongue
English
Weight
419 KB
Volume
17
Category
Article
ISSN
0022-2623

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โœ D. G. Markees; Linda S. Schwab ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 489 KB ๐Ÿ‘ 2 views

## Abstract A modification of the Gouldโ€Jacobs reaction, particularly useful for the preparation of Nโ€alkylโ€4โ€quinoloneโ€3โ€carboxylic acids, is described. Decarboxylation of these acids leads to Nโ€alkylโ€4โ€quinolones or, in the case of Nโ€ethylโ€benzo[h]โ€4โ€quinoloneโ€3โ€carboxylic acid, to 4โ€ethoxyโ€benzo