The drug resistant bacteria pose a severe threat to human health. The increasing resistance of those pathogens to traditional antibacterial therapy renders the identification of new antibacterial agents with novel antibacterial mechanisms an urgent need. In this study, a series of (2S)-N-substituted
✦ LIBER ✦
Synthesis and Antibacterial Activity of Peptide Deformylase Inhibitors †
✍ Scribed by Huntington, Kristi M.; Yi, Tian; Wei, Yaoming; Pei, Dehua
- Book ID
- 124087367
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 117 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0006-2960
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Synthesis and in vitro antibacterial act
✍
Linliang Yu; Weicheng Zhou; Zhenyu Wang
📂
Article
📅
2011
🏛
Elsevier Science
🌐
English
⚖ 285 KB
Design, synthesis and antibacterial acti
✍
Wei Shi; Haikun Ma; Yuejiao Duan; Kelly Aubart; Yuhong Fang; Rimma Zonis; Liping
📂
Article
📅
2011
🏛
Elsevier Science
🌐
English
⚖ 451 KB
ChemInform Abstract: Design, Synthesis a
✍
Wei Shi; Haikun Ma; Yuejiao Duan; Kelly Aubart; Yuhong Fang; Rimma Zonis; Liping
📂
Article
📅
2011
🏛
John Wiley and Sons
⚖ 22 KB
Synthesis and In Vitro Antibacterial Act
✍
Zhenyu Wang; Weicheng Zhou
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 140 KB
Peptide deformylase inhibitors with non-
✍
Seung Kyu Lee; Kwang Hyun Choi; Sang Jae Lee; Jong Sun Lee; Ji Yun Park; B. Moon
📂
Article
📅
2011
🏛
Elsevier Science
🌐
English
⚖ 576 KB
Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis and structure-activity relationship studies of non-peptide PDF inhibitors.
New peptide deformylase inhibitors and c
✍
Goemaere, E.; Melet, A.; Larue, V.; Lieutaud, A.; Alves de Sousa, R.; Chevalier,
📂
Article
📅
2012
🏛
Oxford University Press
🌐
English
⚖ 554 KB