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Synthesis and anti-inflammatory activity of aromatic glucosinolates

โœ Scribed by Vo, Quan V.; Trenerry, Craige; Rochfort, Simone; Wadeson, Jenny; Leyton, Carolina; Hughes, Andrew B.

Book ID
120674406
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
603 KB
Volume
21
Category
Article
ISSN
0968-0896

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A series of acetylenic thiophene derivatives have been synthesized via Pd-catalyzed coupling reaction of 2-(butyltelluro)thiophene with a variety of terminal alkynes. These compounds showed good anti-inflammatory activity in the carrageenininduced paw edema assay on rats.