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Synthesis and anti-inflammatory activity of 2′-phenyl steroidal[17, 16-c]pyrazoles

✍ Scribed by DP Jindal; D Pathak


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
324 KB
Volume
26
Category
Article
ISSN
0223-5234

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Synthesis and anti-inflammatory activity
✍ Gilson Zeni; Cristina W Nogueira; Rodrigo B Panatieri; Dagoberto O Silva; Paulo 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 84 KB

A series of acetylenic thiophene derivatives have been synthesized via Pd-catalyzed coupling reaction of 2-(butyltelluro)thiophene with a variety of terminal alkynes. These compounds showed good anti-inflammatory activity in the carrageenininduced paw edema assay on rats.