Syntheses of substituted 2,4-dioxo-thienopyrimidin-1-acetic acids and their evaluation as aldose reductase inhibitors

N-Substituted Tetrahydro-2,4-dioxoquinaz

N-Substituted Tetrahydro-2,4-dioxoquinazolin-1-yl Acetic Acids as Aldose Reductase Inhibitors.

✍ D. Rakowitz; A. Gmeiner; B. Matuszczak 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 19 KB

Synthesis and Biological Evaluation of 2

Synthesis and Biological Evaluation of 2′-Oxo-2,3-dihydro-3′H- spiro[chromene-4,5′-[1,3]oxazolidin]-3′yl]acetic Acid Derivatives as Aldose Reductase Inhibitors

✍ Simona Rapposelli; Federico Da Settimo; Maria Digiacomo; Concettina La Motta; An 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 1 views

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Evaluation of [2′-Oxo-2,3-dihydro-3′H-spiro[chromene-4,5′- [1,3]oxazolidin]-3′yl]acetic Acid Derivatives as Aldose Reductase Inhibitors.

✍ Simona Rapposelli; Frederico Da Settimo; Maria Digiacomo; Concettina La Motta; A 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 62 KB 👁 1 views

## Abstract A series of the title spirocyclic benzopyran derivatives (XI) (12 examples) is synthesized, which all prove to be selective inhibitors of aldose reductase (ARL2).

ChemInform Abstract: 5-Phenyl Substitute

ChemInform Abstract: 5-Phenyl Substituted 1-Methyl-2-pyridones and 4′-Substituted Biphenyl-4-carboxylic Acids. Synthesis and Evaluation as Inhibitors of Steroid-5α-reductase Type 1 and 2.

✍ Franck Picard; Tobias Schulz; Rolf W. Hartmann 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: 4,1-Benzoxazepine D

ChemInform Abstract: 4,1-Benzoxazepine Derivatives as Squalene Synthase Inhibitors. Part 3. Syntheses of (4,1-Benzoxazepine-3-ylidene)acetic Acid Derivatives and Their Inhibition of Squalene Synthase.

✍ Takashi Miki; Masakuni Kori; Ryu-ichi Tozawa; Masahira Nakamura; Yasuo Sugiyama; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis and Biological Evaluation of 4

Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2

✍ Ola I. A. Salem; Tobias Schulz; Rolf W. Hartmann 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 115 KB 👁 2 views

The synthesis and biological evaluation of 4-(4-(alkyl- and phenylaminocarbonyl)benzoyl)benzoic acids (4a-4d) as non-steroidal inhibitors of steroid 5 alpha-reductase are described. The compounds were tested in vitro for inhibitory activity toward rat and human 5 alpha-reductase isozymes 1 and 2 at