SYNTHESES OF N-CARBOXYMETHYL DIPEPTIDES via N-CARBOXY α-AMINO ACID ANHYDRIDES (NCA) INTERMEDIATES
✍ Scribed by Skiles, Jerry W.; Warus, James D.; Suh, John T.
- Book ID
- 127180397
- Publisher
- Taylor and Francis Group
- Year
- 1988
- Tongue
- English
- Weight
- 280 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0030-4948
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📜 SIMILAR VOLUMES
The polymerization of -y-benzyl+glutamate NCA initiated by n-hexylamine in DMF proceeds with two successive propagation r a h whose ratio is about 1.5. The onset of the increase in rate of propagation occurred a t a DP, of 7-14, which waa independent of initiator to anhydride ratio and anhydride con
## Abstract Oligopeptides were synthesized in high yields by the controlled coupling reaction of __N__‐carboxy α‐amino acid anhydrides (NCA's) with amino acid and peptide sodium salts in the heterogeneous reaction medium of acetonitrile–water which contained sodium carbonate. In this solvent, it co