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Syntheses of deuterium-labelled pristanic and phytanic acids

✍ Scribed by D.W. Johnson; A. Poulos

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
392 KB
Volume
48
Category
Article
ISSN
0009-3084

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✦ Synopsis

The syntheses of tetradeuterated pristanic and phytanic acids, suitable for isotope dilution quantitation of pristanic and phytanic acids in plasma, is described. The key reaction, a Favorsky rearrangement, which simultaneously generates a methyl branch and incorporates deuterium, should be suitable for the preparation of other isotopically-labelled branched chain acids.

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