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Syntheses of deuterated jasmonates for mass spectrometry and metabolism studies

✍ Scribed by Patrycja W. Galka; Stephen J. Ambrose; Andrew R. S. Ross; Suzanne R. Abrams

Publisher
John Wiley and Sons
Year
2005
Tongue
French
Weight
158 KB
Volume
48
Category
Article
ISSN
0022-2135

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✦ Synopsis

Jasmonic acid and its metabolites play an essential role in the regulation of plant development and systemic defense responses. Isotopically labeled standards are required to quantify plant hormones for metabolism studies using mass spectrometry. A convenient method for the preparation of deuterated analogs of jasmonates is demonstrated. Modification of commercially available methyl jasmonate by basecatalyzed proton/deuterium exchange or Wittig reaction introduces either two or three heavy atoms into a molecule.

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