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Syntheses of 18F-labeled reduced haloperidol and 11C-labeled reduced 3-N-methylspiperone

โœ Scribed by Hayden T. Ravert; Robert F. Dannals; Alan A. Wilson; Dean F. Wong; Henry N. Wagner Jr.


Book ID
102374802
Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
306 KB
Volume
29
Category
Article
ISSN
0022-2135

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โœฆ Synopsis


Abstract

^18^Fโ€Labeled reduced haloperidol and ^11^Cโ€labeled reduced 3โ€Nโ€methylspiperone were synthesized in a convenient and quantitative one step reduction from ^18^Fโ€labeled haloperidol and ^11^Cโ€labeled Nโ€methylspiperone, respectively. Both products were purified by semipreparative HPLC and were obtained at high specific activity and radiochemical purity.


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Synthesis of [18F]-labeled N-3(substitut
โœ Mian M. Alauddin; Pradip Ghosh; Juri G. Gelovani ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 143 KB

## Abstract Syntheses of Nโ€3(substituted) analogues of thymidine, Nโ€3([^18^F]fluorobutyl)thymidine ([^18^F]โ€FBT) and Nโ€3([^18^F]fluoropentyl)thymidine ([^18^F]โ€FPT) are reported. 1,4โ€Butane diol and 1,5 pentane diol were converted to their tosyl derivatives **2** and **3** followed by conversion to