Syntheses and antitumor activity of 2-deoxyribofuranosides of 3-deazaguanine
β Scribed by Mian, A. Mohsin; Khwaja, Tasneem A.
- Book ID
- 126438233
- Publisher
- American Chemical Society
- Year
- 1983
- Tongue
- English
- Weight
- 898 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-2623
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π SIMILAR VOLUMES
The syntheses of 2',3'-dideoxy-2',3'-didehydro-~-o-ribofuranoside 1 and 2',3'-dideoxy-3'-fluoro-p-~-ribofuranoside 5 of 7-deazaguanine as well as 7-deaza-2'-deoxyxyloguanosine (3) are described. The corresponding 2,4-diamino compounds 2 and 4 were also prepared. Thus, silylation of 2-amino-4-chloro-
## Abstract ^14^C labeled 2βaminoβ7β(3βpyridylmethyl)β4βoxoβ3__H__,5__H__βpyrrolo[3,2β__d__]pyrimidine(6) was synthesized starting from methyl 3βaminoβ4β(3βpyridylmethyl)β1__H__ βpyrroloβ2βcarboxylate. This pyrrole on condensation with ^14^C labeled benzoylisothiocyanate followed by methylation gav