𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthese neuartiger β-Lactame; 8–Oxo-5–oxa-1-aza-bicyclo-[4,2,0]-octane

✍ Scribed by Lieselotte Paul; Peter Polczynski; Güunter Hilgetag

Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
140 KB
Volume
8
Category
Article
ISSN
0044-2402

No coin nor oath required. For personal study only.

✦ Synopsis

Die als trans-Isomere anfallenden quartaren N-Acylvinyl-Loste VIII bilden farblose, wasserlosliche Verbindungen, die sich gut als schwerlosliche Pikrate charakterisieren lassen (s. Tab. 1). Nucleophile setzen aus VIII unter Aufnahme des Acylvinyl-Restes N-Methyl-Lost, I1 frei.

📜 SIMILAR VOLUMES

Free-radical annelation in the synthesis
Free-radical annelation in the synthesis of bicyclic β-lactams. 1. Synthesis of 8-oxo-5-oxa-1-azabicyclo[4.2.0]octane and 9-oxo-6-oxa-1-azabicyclo[5.2.0]nonane derivatives
✍ Mario D. Bachi; Christian Hoornaert 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 199 KB

A new method for the synthesis of some fused bicyclic B-lactams based on the completion of the molecular backbone by a free-radical C-C bond forming reaction is described. Many of the synthetic approaches to the fused bicyclic molecular backbone of B-lactam antibiotics are based on the annelation of

Synthesis of novel fused β-lactams by in
Synthesis of novel fused β-lactams by intramolecular 1,3-dipolar cycloadditions. 4. 17-phenoxyacetamido-8-oxo-1, 3-diazabicyclo [4.2.0] octane-2-carboxylic acids
✍ Clive L. Branch; Michael J. Pearson 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 185 KB

octane-2-osrbowllc acrds have been synthesised and shown to possess weak antibaoterial activity. We have recently desonbed2 the synthesis of the 8-oxo-l,j-drazabrcyclo [4.2.O] octane ring system. The 7-unsubstltuted free acids (l)3 were antibacterially inactrve, but it was surnusecl that a 7-aoylam