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Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis

✍ Scribed by Kathleen J. Myers; Jonathan Sprent; Joseph P. Dougherty; Yacov Ron


Book ID
119108357
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
769 KB
Volume
41
Category
Article
ISSN
0165-5728

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## Abstract Self antigens bind to MHC class II molecules __in vivo__. The capacity of class II molecules to bind native self antigen, namely antigen that has not been processed through an endososomal pathway, could increase susceptibility to autoimmune diseases if recognized by autoreactive T lymph