Synergistic interaction between measles virus infection and myelin basic protein peptide-specific T cells in the induction of experimental allergic encephalomyelitis in Lewis rats
β Scribed by Uwe G. Liebert; Volker ter Meulen
- Book ID
- 119108627
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 594 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0165-5728
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π SIMILAR VOLUMES
Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a
We have produced T cell lines with a Th2 phenotype in the presence of IL-4 and the glucocorticoid dexamethasone (DEX). IL-4 and DEX together were more effective in inducing a Th2 response than IL-4 alone. Myelin basic protein (MBP)-specific Th2 lines were obtained and their ability to induce experim