Cytokine–neuroantigen fusion proteins: New tools for modulation of myelin basic protein (MBP)-specific T cell responses in experimental autoimmune encephalomyelitis

Mice resistant to experimental autoimmun

Mice resistant to experimental autoimmune encephalomyelitis have increased thymic expression of myelin basic protein and increased MBP specific T cell tolerance

✍ Hong-biao Liu; Allan J MacKenzie-Graham; Sookhyun Kim; Rhonda R Voskuhl 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 513 KB

Synergy between encephalitogenic T cells

Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis

✍ Kathleen J. Myers; Jonathan Sprent; Joseph P. Dougherty; Yacov Ron 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 769 KB

Induction of myelin basic protein-specif

Induction of myelin basic protein-specific experimental autoimmune encephalomyelitis in C57BL/6 mice: Mapping of T cell epitopes and T cell receptor Vβ gene segment usage

✍ M.K. Shaw; C. Kim; H.W. Hao; F. Chen; H.Y. Tse 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 966 KB

Early studies of murine experimental autoimmune encephalomyelitis (EAE) induced with myelin basic protein (MBP) divide various mouse strains into either "susceptible" or "resistant" phenotypes. Resistance is defined as lack of encephalitogenic responses after active immunization or adoptive transfer

CD40-mediated activation of T cells acce

CD40-mediated activation of T cells accelerates, but is not required for, encephalitogenic potential of myelin basic protein-recognizing T cells in a model of progressive experimental autoimmune encephalomyelitis

✍ Sara Abromson-Leeman; Emanual Maverakis; Roderick Bronson; Martin E. Dorf 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 1 views

Defective T helper cell epitope responsi

Defective T helper cell epitope responsible for the failure of region 69–84 of the human myelin basic protein to induce experimental allergic encephalomyelitis in the lewis rat

✍ G. A. Hashim; A. B. Galang; J. V. Srinivasan; E. F. Carvalho; H. Offner; A. A. V 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 857 KB

Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a

Analysis of the T cell repertoire for my

Analysis of the T cell repertoire for myelin basic protein in thymus-grafted and other types of chimera: evidence that major histocompatibility complex molecules on accessory cells rather than T cell specificity mainly regulate susceptibility to autoimmune encephalomyelitis

✍ Yoh Matsumoto; Kazuhiro Kawai; Michio Fujiwara 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 860 KB

Analysis of the T cell repertoire for myelin basic protein in thymus-grafted and other types of chimera: evidence that major histocompatibility complex molecules on accessory cells rather than T cell specificity mainly regulate susceptibility to autoimmune encephalomyelitis\* Experimental autoimmune