## Abstract __Purpose__: To investigate the association of matrix metalloproteinase‐9 (MMP‐9) and paraoxonase 1 (PON1) 192 polymorphisms with susceptibility to coronary artery stenosis (CAS) and the number of diseased vessels in patients with CAS. __Methods__: The study population comprised 302 unr
✦ LIBER ✦
Synergistic Effects between Q192R Polymorphism of Paraoxonase 1 Gene and Some Conventional Risk Factors in Premature Coronary Artery Disease
✍ Scribed by Anna Balcerzyk; Iwona Zak; Jolanta Krauze
- Book ID
- 113467096
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 102 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0188-4409
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## Abstract Paraoxonase 1 (PON 1) is a high‐density lipoprotein (HDL)‐associated enzyme with antioxidant function protecting low‐density lipoprotein (LDL) from oxidation. PON 1 has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These polymorphisms modulate paraoxonase activity o