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Association of the paraoxonase-1 Q192R polymorphism with coronary artery disease in AMI patients, non AMI CAD patients and healthy controls


Book ID
117638610
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
137 KB
Volume
14
Category
Article
ISSN
0939-4753

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## Abstract Paraoxonase 1 (PON 1) is a high‐density lipoprotein (HDL)‐associated enzyme with antioxidant function protecting low‐density lipoprotein (LDL) from oxidation. PON 1 has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These polymorphisms modulate paraoxonase activity o