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Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113)

✍ Scribed by Ping Zhang; Qin Xu; Wan Tao Chen; Li Qiong Duan; Zhi Yuan Zhang; Xiao Jian Zhou


Book ID
113832584
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
204 KB
Volume
41
Category
Article
ISSN
1368-8375

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## Abstract Oral squamous cell carcinoma (OSCC) may arise from potentially malignant oral lesions. All‐__trans__ retinoic acid (atRA), which plays a role in cell growth and differentiation, has been studied as a possible chemotherapeutic agent in the prevention of this progression. While the mechan