## Abstract __NKX3.1__ is a homeobox gene, expression of which is largely restricted to the adult prostatic epithelium. Loss of NKX3.1 expression has been linked to prostate carcinogenesis and disease progression and occurs in the absence of mutations in the coding region of the __NKX3.1__ gene. In
β¦ LIBER β¦
Regulation of apoptosis-related molecules by synergistic combination of all-trans retinoic acid and zoledronic acid in hormone-refractory prostate cancer cell lines
β Scribed by Bulent Karabulut; Burcak Karaca; Harika Atmaca; Asli Kisim; Selim Uzunoglu; Canfeza Sezgin; Ruchan Uslu
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 398 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0301-4851
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## Abstract Allβtrans retinoic acid (ATRA), a synthetic derivative of vitamin A, inhibits the growth of breast cancer cells. To elucidate the mechanism by which ATRA causes cell growth inhibition, we examined changes in cell cycle and intracellular signaling pathways, focusing on protein kinase C (