Crude (P2) synaptosomes derived from rats with acute hepatic encephalopathy (HE) induced with thioacetamide showed a slightly increased uptake of radiolabeled arginine (ARC) and a 2.5-fold enhanced conversion of newly taken-up ARC to both glutamate (GLU) and y-aminobutyric acid (GABA) as compared wi
Synaptosomal glutamate transport in thioacetamide-induced hepatic encephalopathy in the rat
β Scribed by Kofi N. W. Oppong; Kim Bartlett; Christopher O. Record; Hanan Al Mardini
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 741 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0270-9139
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Functional changes of various neurotransmitter systems have been implicated in the pathogenesis of hepatic encephalopathy. In this study the role of brain monoaminergic neurotransmitter systems in hepatic encephalopathy was investigated in rats with thioacetamide-induced acute liver failure. Concent
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