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Surfactant self-assembly objects as novel drug delivery vehicles

โœ Scribed by Calum J Drummond; Celesta Fong


Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
838 KB
Volume
4
Category
Article
ISSN
1359-0294

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โœฆ Synopsis


The past decade has been witness to a new impetus in surfactant self-assembly objects as agents for drug delivery that are an alternative to micellar, lamellar (liposome, niosome and transfersome) or microemulsion-based vehicles. The review focus herein is on the application of hexagonal, cubic, 'intermediate' (viz. rhombohedral, tetragonal and monoclinic) and L, ('sponge') mesophases.


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## Abstract A novel amphiphilic fourโ€armed [poly(__ฮต__โ€benzyloxycarbonylโ€Lโ€lysine)]~2~__โ€blockโ€__poly(ethylene glycol)__โ€blockโ€__[poly(__ฮต__โ€benzyloxycarbonylโ€Lโ€lysine)]~2~ hybrid copolymer has been prepared. The cytotoxicity study shows that the copolymer has good biocompatibility with no obvious