Synthesis and self-assembly behavior of novel polyaspartamide derivatives for anti-tumor drug delivery

Synthesis and self-assembly of amphiphil

Synthesis and self-assembly of amphiphilic poly(acrylic acid-b-dl-lactide) to form micelles for pH-responsive drug delivery

✍ Ya-Nan Xue; Zhen-Zhen Huang; Jian-Tao Zhang; Min Liu; Min Zhang; Shi-Wen Huang; 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 456 KB

An amphiphilic diblock copolymer of poly(acrylic acid-b-DL-lactide) (PAAc-b-PDLLA) was synthesized by ring-opening polymerization of DL-lactide initiated by hydroxyl-terminated polyacrylic acid (PAAc-OH). The critical micelle concentration (CMC) of PAAc-b-PDLLA in aqueous solution, determined by flu