This study was performed to test whether monocrotaline (MCT)-induced early airway dysfunction and gas exchange abnormalities result in arterial hypoxemia. Thirty young male Sprague-Dawley rats were divided into four groups: control, MCT1, MCT2, and MCT3. Each of the control animals was injected (sub
Surfactant disposition in rats with monocrotaline-induced pneumotoxicity
โ Scribed by Paul M. Bummer; Jennifer A. Baughn; Lynda P. Sanders; Kristi R. Absher; William N. O'Connor; Jack W. Olson; Mark N. Gillespie
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 506 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In this study, the effects of chronic administration of tetrandrine (TET) on monocrotaline (MCT) induced pulmonary hypertension were investigated. The results showed that MCT induced marked pulmonary hypertension and right ventricular hypertrophy; TET 50 mg kg-' and 100 mg kg-' significantly decreas
The profile of urinary salicylate metabolites was determined after an oral administration of acetylsalicylic acid (ASA) to: 1, control rats; 2, rats treated with C C 4 and 3, rats intoxicated with C C 4 and also pretreated with colchicine for 7 days. The following enzymatic activities were determine
The effects of the calcium entry blocking drug, felodipine, were examined against the spasmogens, noradrenaline, 5-hydroxytryptamine (5-HT) and endothelin on pulmonary artery preparations taken from rats treated with saline or monocrotaline (endothelium present) and from untreated rats (endothelium