Suramin blocks growth-stimulatory effects of platelet-derived growth factor on malignant fibrous histiocytomas in vitro
✍ Scribed by Avni Abdiu; Sven-Erik Larsson; Åke Wasteson; Thomas M. Walz
- Book ID
- 117469617
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 86 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0304-3835
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Platelet-derived growth factor (PDGF) is a polypeptide found in a variety of tissues, including bone, where it could act as an autologous regulator of skeletal remodeling. Therefore, a recombinant B chain homodimer of human PDGF was studied for its effects on bone formation in cultured rat calvariae
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