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Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells

โœ Scribed by Shur-Hueih Cherng; Shih-Lan Hsu; Jia-Ling Yang; Chang-Tze Ricky Yu; Huei Lee

Book ID
119378253
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
290 KB
Volume
161
Category
Article
ISSN
0378-4274

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Sudan III dye strongly induces CYP1A1 mR
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โœ Marumi Ohno; Yoshinori Ikenaka; Mayumi Ishizuka ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 219 KB

## Abstract Sudan dyes possess a high affinity to the aryl hydrocarbon receptor (AHR) and potently induce its target genes, such as cytochrome P450 (CYP) 1A1, through unknown mechanisms. We investigated a detailed event occurring in cells after binding of Sudan dye to AHR in HepG2 cells. Treatment