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Suppression of bile acid synthesis, but not of hepatic cholesterol 7α-hydroxylase expression, by obstructive cholestasis in humans

✍ Scribed by Marco Bertolotti; Lucia Carulli; Mauro Concari; Pietro Martella; Paola Loria; Enrico Tagliafico; Sergio Ferrari; Marina Del Puppo; Barbara Amati; Emma De Fabiani; Maurizio Crestani; Claudio Amorotti; Antonio Manenti; Francesca Carubbi; Adriano Pinetti; Nicola Carulli


Book ID
111721560
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
129 KB
Volume
34
Category
Article
ISSN
0270-9139

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Bile acids exert negative feedback contr
✍ Jaap Kwekkeboom; Dr. Hans M. G. Princen; Eline M. van Voorthuizen; Dr. Herman Ja 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 847 KB

Feedback regulation of bile acid synthesis by its end products was studied in cultured hepatocytes of young weaned pigs. We previously showed that conversion of exogenous ["Cl cholesterol into bile acids was suppressed by addition of bile acids to the culture medium. In the present study, the effec