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Sulfone-Mediated Total Synthesis of (±)-Lepadiformine

✍ Scribed by John J. Caldwell; Donald Craig


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
127 KB
Volume
119
Category
Article
ISSN
0044-8249

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Sulfone-Mediated Total Synthesis of (±)-
✍ John J. Caldwell; Donald Craig 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB 👁 2 views

À)-Lepadiformine ( 1) is a decahydro-1H-pyrrolo[1,2-j]quinoline isolated in 1994 by Biard et al. from the tunicate Clavelina lepadiformis. [1] Lepadiformine has moderate in vitro cytotoxic activity towards various tumor cell lines, including nonsmall-cell lung carcinoma (NSCLC-N6), and is also a car