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Sulfone-Mediated Total Synthesis of (.+-.)-Lepadiformine (I).

โœ Scribed by John J. Caldwell; Donald Craig


Publisher
John Wiley and Sons
Year
2007
Weight
12 KB
Volume
38
Category
Article
ISSN
0931-7597

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ร€)-Lepadiformine ( 1) is a decahydro-1H-pyrrolo[1,2-j]quinoline isolated in 1994 by Biard et al. from the tunicate Clavelina lepadiformis. [1] Lepadiformine has moderate in vitro cytotoxic activity towards various tumor cell lines, including nonsmall-cell lung carcinoma (NSCLC-N6), and is also a car

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