Suicide gene therapy for pediatric tumors
β Scribed by Christian Beltinger; Wolfgang Uckert; Klaus-Michael Debatin
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 132 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A low-dose maintenance schedule of Adriamycin was evaluated in six children whose metastatic solid tumors regressed following toxic induction therapy with Adriamycin. Three of these children are now disease-free more than one year following discontinuation of therapy. Adriamycin can be given on a lo
Background. Sixteen pediatric patients with solid tumors received treatment on a protocol designed to test the feasibility and safety of high-dose rate intraoperative radiation therapy (IOHDR) via a remote afterloader. Patients and Methods. Patients with Ewing's sarcoma (n = 5), rhabdomyosarcoma (n
Tumor cells genetically modified with the herpes simplex virus thymidine kinase (HSV-tk) gene in combination with ganciclovir (GCV) demonstrate a ''bystander effect''. Previous attempts to enhance the bystander tumor killing by combining cytokine genes with HSV-tk/GCV have met with varying results.