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Sugar–Oligoamides: Synthesis of DNA Minor Groove Binders

✍ Scribed by Badı́a, Concepción; Souard, Florence; Vicent, Cristina

Book ID
118010822
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
619 KB
Volume
77
Category
Article
ISSN
0022-3263

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## Abstract Solid‐phase procedures have been used to prepare six dipyrrole‐containing DNA ligands that combine (guanin‐9‐yl)acetyl, (guanin‐7‐yl)acetyl or acetyl moieties at the N‐terminal end and two lysines or a (dimethylamino)propyl group at the C terminus. Inspection of their DNA‐stabilizing pr