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Expanding DNA Sequence Recognition with Minor Groove Binders

✍ Scribed by Munde, Manoj M.; Kumar, Arvind; Nhili, Raja; Depauw, Sabine; David-Cordonnier, Marie-Helen; Boykin, David; Wilson, David

Book ID
122182758
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
51 KB
Volume
100
Category
Article
ISSN
0006-3495

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## Abstract Solid‐phase procedures have been used to prepare six dipyrrole‐containing DNA ligands that combine (guanin‐9‐yl)acetyl, (guanin‐7‐yl)acetyl or acetyl moieties at the N‐terminal end and two lysines or a (dimethylamino)propyl group at the C terminus. Inspection of their DNA‐stabilizing pr