Highly enantioselective hydrolyses of syn-3-acetoxy-2-methyl ester and anti-3-acetox.y-Z-methyl esters with lipase "Amano A" and lioase "Amano A-6" isolated from Aspergillus-niger, are described. In the synthetic studies of erythronolide A, it was required to prepare (2R,3R)-2,4-dimethyl-3-hydroxy-4
β¦ LIBER β¦
Subtilisin-catalyzed hydrolysis of peptide methyl esters
β Scribed by Manfred Philipp; Myron L. Bender
- Book ID
- 115904679
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 141 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0014-5793
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## Previous work of Hansson and Rasmusson (1) has shown that low concentrations (lO-' M) of ascorbic acid enhance the rate of purified milk acid phosphatase catalyzed hydrolysis of phenyl phosphate by 500/o, and that higher concentrations of ascorbic acid (lo-'M) are completely inhibitory. It was